; Stellato et al. In conclusion, existing studies provide insight into the gender-based differences in patients undergoing catheter ablation for atrial fibrillation as it pertains to heart failure. The goal of personalized and patient-centered approach to cardiovascular medicine should fully integrate the context of care and individual characteristics, such as gender, ethnicity, culture, health literacy, education level, income, and geography. 1 to 7; 2014 to 2020; 2019 to 2020: v.6 2019: v.7 2020: 2014 to 2018: v.1 2014: v.2 2015: v.3 2016: v.4 2017: v.5 2018: Articles from Frontiers in Cardiovascular Medicine are provided here courtesy of Frontiers … Medicine Cardiology and Cardiovascular Medicine: Publisher: Frontiers Media S.A. Compared with historical Journal Impact data, the Metric 2019 of Frontiers in Physiology dropped by … Over the past decade, clinical data has also shown that certain modern medications may be harmful when applied to heart failure patients (2). The next step in this bench-to-bedside approach is to validate any beneficial effects of these potential therapeutic agents in a living organism. A review paper by Oppi et al. The mammalian SPP/SPPL family of intramembrane cleaving proteases consists of five members: SPP and its homologous proteins SPPL2a, SPPL2b, SPPL2c, and SPPL3. As long-term follow-up data mainly derive from old studies with early generation devices on high or intermediate surgical risk patients, results can hardly be extended to most of currently treated patients who often show a low surgical risk and are treated with newer generation prostheses. Led by an outstanding Editorial Board of … Registry data-based studies assessing sex-related differences in atrial fibrillation catheter ablation in heart failure reveal that women are half as likely as men to undergo ablation. The Cardio-Oncology section of Frontiers in Cardiovascular Medicine is to provide a prime publication platform for this emerging field in medicine. The primary outcomes evaluated were freedom from recurrent atrial tachyarrhythmia (ATa), severity of MR, and left atrial (LA) and LV remodeling.Results: During a mean follow-up of 20.7 ± 16.8 months, freedom from recurrent ATa was not significantly different between patients with LVSD and those with normal LVF after the first ablation (P = 0.301) and after multiple ablations (P = 0.728). Scope. As TAVR was progressively studied and clinically used in lower-risk patients, issues were raised questioning its opportunity in a younger population with a longer life-expectancy. Recent studies have unveiled that myocardial hypertrophic preconditioning (HP), which is produced by de-banding (De-TAC) of short-term transverse aortic constriction (TAC), protects the heart against hypertrophic responses caused by subsequent re-constriction (Re-TAC) in mice. In the last decades, transcatheter aortic valve replacement (TAVR) revolutionized the treatment of symptomatic severe aortic stenosis. In the second, Daskalopoulos et al. The primary and secondary endpoints were cardiac death and all-cause mortality, respectively.Results: Baseline PA levels were significantly higher in male patients than in female patients (11.40 ± 5.83% vs. 9.93 ± 5.49%, P = 0.001). Frontiers in Cardiovascular Medicine is a global, peer-reviewed Open Access medical journal providing unrestricted, online access to publications on diagnostic and therapeutic advances in cardiology and cardiovascular disease.Frontiers in Cardiovascular Medicine … Myofibrils are traditionally obtained from a small section of cardiac muscle and their isolation from cultured cardiomyocytes opens new opportunities for the in vitro manipulation of cultured cells prior to the isolation of myofibrils. Male C57BL/6J mice (10–12 weeks old) were randomly subjected to Sham, HP [TAC for 3days (TAC 3d), de-banding the aorta for 4 days (De-TAC 4d), and then re-banding the aorta for 4 weeks (Re-TAC 4W)], and TAC (TAC for 4 weeks without de-banding). ; Zuppinger) and animal models (Bacmeister et al. The Journal Impact Quartile of Frontiers in Physiology is Q2. Original research articles include manuscripts reporting results from clinical investigations, including Phase I-III trials and population studies. Frontiers in Cardiovascular Medicine publishes peer-reviewed research articles across basic, translational, and clinical cardiovascular medicine. The section Cardiovascular Genetics and Systems Medicine concentrates on papers covering a range of topics in all aspects of cardiovascular genetics with a special emphasis on systems medicine … Males had higher predictive PA cut-off values for cardiac death (11.16 vs. 7.15%) and all-cause mortality (11.33 vs. 7.17%). present a new approach to identifying and isolating murine cardiac fibroblasts using simple two-color flow cytometry. Within the eight existing randomized controlled trials on heart failure with reduced ejection fraction, women composed a small proportion of the study population. The Journal Impact 2019-2020 of Frontiers in Physiology is 3.160, which is just updated in 2020. Sex should be considered as an important contributing factor when deciding for PA targets. The authors go on to describe the inherent weaknesses associated with a single animal study due to the high number of uncontrollable variables (Daskalopoulos et al.). 7:630993. doi: 10.3389/fcvm.2020.630993 Received: 19 November 2020; Accepted: 20 November 2020; Published: 14 December 2020. Because atherosclerosis can be induced in several atherosclerosis-prone genetic mouse strains by different mechanisms, the paper provides a road map for researchers to choose the most appropriate model for a specific scientific question (Oppi et al.). journal. Frontiers journals lead in citations & rank in the top Impact Factor and CiteScore percentiles. Frontiers in Laboratory Medicine publishes rigorously peer-reviewed, high-quality original articles and authoritative reviews that focus on developments and advances in laboratory medicine. According to the 1997 World Health Report, 15 million deaths (i. e. 30% of the total number of deaths) were attributable to cardiovascular … The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. This study investigated the clinical impact of OM load in femoral artery plaques of patients with lower extremity artery disease (LEAD) by using a deep learning-based image analysis algorithm. These data underscore the difficulty of assessing animal studies where the complexity of living organisms and the variability of housing conditions can affect outcomes. The purpose of this study is to assess the production of nitric oxide in professional cross-country skiers with normotensive and hypertensive responses to physical activity at maximum load. Compared with historical Journal Impact data, the Metric 2019 of … Conflicting data exist on the interaction of gender and heart failure as they may affect peri-ablation and post-ablation long-term outcomes such as atrial fibrillation recurrence or heart failure hospitalizations. Based on studies in cell culture models various substrates of SPP/SPPL proteases have been identified in the past years and recently-developed mouse lines lacking individual members of this protease family, will help to further clarify the physiological functions of these proteases. During the median follow-up time of 75.7 ± 29.1 months, patients with baseline PA